The Year is 2006, The Drug Trade is Booming, Trafficking Between Asia and Europe is at an all time high. It is at this time that the Malaysian Intelligence and Anti-Narcotic Departments are called upon for assistance by their Indian Counterparts. There are rumours that the gang have recently moved their operational Headquarters to KL. The cartel
is headed by the dreaded, Singhania (Rajesh Khattar). But what many people do not know, is that the business is truly managed by his trusted lieutenant, Don.
A man who lives life on the edge, Don is constantly expanding the size of his Empire while evading arrest or death at the hands of enemies, Both within and outside the law. Fearless, cunning and ruthless, he is unstoppable in his pursuit of absolute power.
His Chief Pursuer is an Indian Police Officer Narcotics, DCP DeSilva(Boman Irani). He is a man who has sworn to put an end to this nexus of evil and knows that in capturing Don lies the key to unlock this puzzle, and one day, he succeeds. Don is captured and DeSilva puts his plan into action.
Unknown to even his own Department, DeSilva has captured and trained a man who is a spitting image of Don. His name is Vijay(Shah Rukh Kahn).
Vijay inflitrates the cartel and manages to give DeSilva all the information he needs to bring it down. But in a Bizarre
twist of fate, DeSilva is killed during a raid and the secret that Don is infact, Vijay, a police informer, is buried with him, the only peoples who realize that he is infact an imposter, are the members of Don's cartel, and they want their revenge.
Vijay manages to escape and is now on the lookout for the one last piece of evidence that can get him out of this mess.
Helping him on this quest are two people, the first is Roma(Priyanka Chopra): A young woman, who has working in the gang but only to avenge her brother's death. He had been mercilessly killed by Don when he had decided to leave the gang. The other is Jasjit(Arjun Rampal): the real father of Vijay's adopted son, Deepu, he owes Vijay for having looked after the boy while he was in prison.
Wanted by the police, haunted day and night, forever on the run... The Chase Has Begin.